In order to further investigate the quantifying capacity of the Fe 3 O 4 C nanoflowers, the magnetic lateral flow immunoassay was tested as a detection system for extracellular vesicles (EVs), a novel source of biomarkers with interest for liquid biopsy.

Next Article in Journal Development of an Electrochemical Immunosensor for Specific Detection of Visceral Leishmaniasis Using Gold-Modified Screen-Printed Carbon Electrodes.

Next Article in Special Issue DNAGold Nanozyme-Modified Paper Device for Enhanced Colorimetric Detection of Mercury Ions.

Previous Article in Journal Skin-Integrated Wearable Systems and Implantable Biosensors: A Comprehensive Review.

Previous Article in Special Issue Detection of Cardiovascular CRP Protein Biomarker Using a Novel Nanofibrous Substrate.

Please note that many of the page functionalities wont work as expected without javascript enabled.

European Journal of Investigation in Health, Psychology and Education (EJIHPE).

International Journal of Environmental Research and Public Health (IJERPH).

Journal of Open Innovation: Technology, Market, and Complexity (JOItmC).

Journal of Theoretical and Applied Electronic Commerce Research (JTAER).

Find support for a specific problem in the support section of our website.

Please let us know what you think of our products and services.

Visit our dedicated information section to learn more about MDPI.

Carbon-Coated Superparamagnetic Nanoflowers for Biosensors Based on Lateral Flow Immunoassays.

Received: 22 June 2020 Revised: 9 July 2020 Accepted: 18 July 2020 Published: 22 July 2020.

The strips were examined after use in the detection device.

X-ray spectroscopy (EDS) spectrum obtained from one particular location in a SEM image of the strips with presence of Fe 3 O 4 C nanoparticles.

Superparamagnetic iron oxide nanoflowers coated by a black carbon layer (Fe 3 O 4 C) were studied as labels in lateral flow immunoassays.

They were synthesized by a one-pot solvothermal route, and they were characterized (size, morphology, chemical composition, and magnetic properties).

They consist of several superparamagnetic cores embedded in a carbon coating holding carboxylic groups adequate for bioconjugation.

Their multi-core structure is especially efficient for magnetic separation while keeping suitable magnetic properties and appropriate size for immunoassay reporters.

Their functionality was tested with a model system based on the biotinneutravidin interaction.

For this, the nanoparticles were conjugated to neutravidin using the carbodiimide chemistry, and the lateral flow immunoassay was carried out with a biotin test line.

Quantification was achieved with both an inductive magnetic sensor and a reflectance reader.

Abi Boardmaster 4000 Test Leads